Wednesday, February 02, 2005

PBS approval process goes west with new FTA

The PBS approved two new drugs for schizophrenia and bi-polar disorder today. And it's an indication of what may be to come.
One of these drugs, Zyprexa, has been linked to a significant increase in the risk of diabetes amongst people taking it. In fact, it's dubious improved efficacy (as compared to similar drugs) and it's price (twice that of older drugs) are the centrepiece of allegations regarding ties between it's manufacturer, Eli-Lilly and the Bush Adminstration.
The other drug, risperdal consta, is an older(introduced in the 1990's) anti-psychotic in a new long acting form.It uses an innovative new form of sustained release encapsulation which enables it to be given up fortnightly instaed of daily. But, although, it is an 'atypical anti-psychotic' it still has typical symptoms that it shares with the older anti-psychotics such as librium and haloperidol. Anecdotal evidence suggests that it is the most likely of these newer anti-psychotics to have 'extra-pyramidal syndromes'. These are involuntary movements, that can be quite severe and can lead to permanent disabilities.
Whilst one can make out a case for the latter drug(the long acting formulation is an innovation), the case for zyprexa is surely contentious. Is this a sign of things to come?

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Blogger Danny Haszard said...

I applaud your blog,i took zyprexa which was ineffective for my condition and gave me diabetes.

{Only 9 percent of adult Americans think the pharmaceutical industry can be trusted right around the same rating as big tobacco}

Zyprexa, which is used for the treatment of psychiatric disorders, such as schizophrenia and bipolar disorder, accounted for 32% of Eli Lilly's $14.6 billion revenue last year.

Zyprexa is the product name for Olanzapine,it is Lilly's top selling drug.It was approved by the FDA in 1996 ,an 'atypical' antipsychotic a newer class of drugs without the motor side effects of the older Thorazine.Zyprexa has been linked to causing diabetes and pancreatitis.

Did you know that Lilly made nearly $3 billion last year on diabetic meds, Actos,Humulin and Byetta?
Yes! They sell a drug that causes diabetes and then turn a profit on the drugs that treat the condition that they caused in the first place!

I was prescribed Zyprexa from 1996 until 2000.
In early 2000 i was shocked to have an A1C test result of 13.9 (normal is 4-6) I have no history of diabetes in my family.
Daniel Haszard

5:12 am  

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